Lupus Site - a guide for lupus patients and their families

These are other antibodies to proteins in the nuclei.

Includes -

� � �- anti-Sm

� � �- anti-Ro (especially associated with lupus skin disease, heartblock in neonates and Sj�grens syndrome. It can 'leak' across the placenta and lead to slow heartbeat in the developing foetus: this can require a 'blood change' as soon as the baby is born.)

� � �- anti-La (SLE, Sj�grens syndrome)

� � �- anti-RNP (if present with antibodies to DNA, then diagnosis is SLE, if present alone, then diagnosis is mixed connective tissue disease, MCTD)

� � �- Anti-Scl70 (systemic sclerosis)

� � �- Anti-Jol (polymyositis)

� � �- And others